2个月2292就耐药，有点担心！
谁知道，YL2992与正版的阿法替尼有多大差别？
找找中药，可能不到调理有用，病情有稳定。
一定要做好准备,一是做好对副作用的应对;二是做好YL版的混装;三是要多了解靶向药的知识;四是多备几种靶向药,感谢憨叔和老马!
LUX-LUNG 4
The phase II LUX-LUNG 4 trial gives further support to the idea that afatinib may be a good option for patients who develop that T790M resistance mutation following treatment with other TKIs. Researchers led by Nobuyuki Katakami, MD, PhD, of Kobe City Medical Center General Hospital in Kobe, Japan, treated 62 patients who were EGFR-mutation positive in the primary tumor with afatinib at 50 mg/day. Fifty-one of the patients (82.3%) qualified as having acquired resistance to erlotinib and/or gefitinib.
Of the 61 patients who were evaluable, five (8.2%) had a confirmed objective response to afatinib. The median progression-free survival was 4.4 months, with a median overall survival of 19 months. Among the afatinib-related adverse events, all patients experienced diarrhea and most (91.9%) had rash/acne; 29% of patients had an adverse event that led to discontinuation of the drug.
“The results of our trial demonstrated modest but noteworthy activity of afatinib in this difficult-to-treat population,” the authors wrote. They noted that further trials are now ongoing, including one phase IB trial testing the combination of afatinib and cetuximab(Drug information on cetuximab) in a small number of patients. “There is an increasing need to develop new molecular targeted agents that address the issue of resistance to erlotinib and/or gefitinib in patients with NSCLC who initially respond to treatment and then subsequently progress.”
请问哪里有卖2992
学习了很多，收获很多。
目前，美国和台湾都有正版的，澳门年底能审批下来。
zhangbohai 发表于 2013-4-2 15:07 static/image/common/back.gif
我爸爸吃了这个药非常有效，谢谢！
请告知一下2992 购买渠道，急用！非常感谢。
肺腺癌IV期，请问哪能买2992，就急呀，知到的朋友给指条路好么！！！！跪谢。